Study queStion Does the 23-valent pneumococcal polysaccharide vaccine prevent pneumonia and improve survival in nursing home residents? Summary anSwer
نویسندگان
چکیده
Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Japan Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Japan Department of Immunology, Mie University Graduate School of Medicine, Edobashi 2-174, Tsu City, Mie Prefecture, Japan Kinan General Hospital, Minamimuro, Mie, Japan Division of Hematology, Stanford School of Medicine, Stanford, CA, USA Department of Medicine, Winthrop University Hospital, Mineola, NY, USA correspondence to: E C Gabazza [email protected]
منابع مشابه
Efficacy of 23-valent pneumococcal vaccine in preventing pneumonia and improving survival in nursing home residents: double blind, randomised and placebo controlled trial
OBJECTIVE To determine the efficacy of a 23-valent pneumococcal polysaccharide vaccine in people at high risk of pneumococcal pneumonia. DESIGN Prospective, randomised, placebo controlled double blind study. SETTING Nursing homes in Japan. PARTICIPANTS 1006 nursing home residents. INTERVENTIONS Participants were randomly allocated to either 23-valent pneumococcal polysaccharide vaccine ...
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S. pneumoniae is a significant cause of community-acquired pneumonia in the elderly, and accounts for the majority of the pneumonia deaths among the elderly. We conducted this randomized double-blind study to evaluate the immune response to a 23-valent pneumococcal polysaccharide vaccine and the persistence of antibodies two years after the vaccination in an elderly population in Santiago, Chil...
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Background: Pneumococcal vaccine provides protection against invasive pneumococcal disease in population at risk. This study was conducted to compare the antibody response to 13-valent pneumococcal conjugate vaccine and 23-valent pneumococcal polysaccharide vaccine in patients with thalassemia major. Methods: A randomized cross-over clinical trial was performed on 50 asplenic patients with t...
متن کاملPrevention of mortality and pneumonia among nursing home older adults by dual pneumococcal and seasonal influenza vaccination during a pandemic caused by novel pandemic influenza A (H1N1).
OBJECTIVE To evaluate the efficacy of dual vaccination of seasonal influenza and pneumococcus in nursing home older adults during a novel pandemic of influenza A (H1N1). SETTING Nine nursing homes in Hong Kong. PARTICIPANTS A total of 532 nursing home older adults were included in the study. MEASUREMENTS Efficacy of dual vaccination of seasonal influenza and pneumococcus in nursing home o...
متن کاملEffectiveness of the polysaccharide pneumococcal vaccine among HIV-infected persons in Brazil: a case control study
BACKGROUND Polysaccharide pneumococcal vaccine is recommended for use in HIV-infected adults in Brazil but there is uncertainty about its effectiveness in this patient population. The main objective of this study was to assess the effectiveness of the 23-valent polysaccharide pneumococcal vaccine against invasive pneumococcal infection among HIV-infected adult patients in São Paulo, Brazil. M...
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